Biochemical bone markers and biological effects of osteoporosis therapy
نویسندگان
چکیده
منابع مشابه
[Biochemical bone markers and biological effects of osteoporosis therapy].
Osteoporoza je poreme aj skeleta u ijoj osnovi se nalazi poreme aj koštane vrstine koji vodi pove anju rizika od fraktura. Koštana snaga, odnosno vrstina, integriše koštani kvantitet (mineralna gustina, pre nik kosti, debljina korteksa) i kvalitet (mikroarhitektonika, koštani promet) . Više od 1,5 miliona vertebralnih i nevertebralnih fraktura javlja se na bazi osteoporoze od koje u svetu boluj...
متن کاملBone markers and osteoporosis therapy.
Several factors are involved in determining bone quality including bone density, bone turnover, the extent of trabecular bone connectivity, cortical porosity and geometry. Metabolically active and in a continuous process of remodeling, approximately 20% of bone tissue is renewed annually. Bone turn over markers (BTM) are frequently used in clinical trials and to provide valid information about ...
متن کاملBiochemical markers of bone turnover and osteoporosis management
Marius Kraenzlin turnover. Bone mass can be assessed by measuring bone mineral density (BMD) using dual X-ray absorptiometry (DXA), and there is a large body of evidence that low BMD is an important determinant of fracture risk [1– 3]. There is a consistent doubling of fracture risk for each SD reduction in BMD, irrespective of fracture type and BMD measurement site. However, there is no thresh...
متن کاملBiochemical markers of bone turnover and their utility in osteoporosis.
O steoporosis, an age-related, degenerative disease of bone is an asymptomatic disease that is diagnosed after an already unacceptable loss of bone has occurred. Alternatively, a compression fracture may lead to the initial diagnosis. Diagnosis is established by bone mineral density (BMD) at the hip and/or spine.1 BMD is a static measure of bone composition, reflecting its “history,” and detect...
متن کاملRole of biochemical markers of bone turnover as prognostic indicator of successful osteoporosis therapy.
Most of the currently available anti-osteoporosis medications promptly and significantly influence the rate of bone turnover. Biochemical markers of bone turnover now provide a high sensitivity to change, allowing the detection of these bone turnover changes within a couple of weeks. Since the anti-fracture efficacy of inhibitors of bone resorption or stimulators of bone formation appears to be...
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ژورنال
عنوان ژورنال: Military Medical and Pharmaceutical Journal of Serbia
سال: 2012
ISSN: 0042-8450,2406-0720
DOI: 10.2298/vsp1205432k